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Artemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in mice

Calorie restriction is known to extend lifespan among organisms by a debating mechanism underlying nitric oxide-driven mitochondrial biogenesis. We report here that nitric oxide generators including artemisinin, sodium nitroprusside, and L-arginine mimics calorie restriction and resembles hydrogen p...

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Detalles Bibliográficos
Autores principales: Wang, Da-Ting, He, Jiang, Wu, Ming, Li, Si-Ming, Gao, Qian, Zeng, Qing-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358698/
https://www.ncbi.nlm.nih.gov/pubmed/25780774
http://dx.doi.org/10.7717/peerj.822