The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes

Most mutations that compromise meiotic recombination or synapsis in mouse spermatocytes result in arrest and apoptosis at the pachytene stage of the first meiotic prophase. Two main mechanisms are thought to trigger arrest: one independent of the double-strand breaks (DSBs) that initiate meiotic rec...

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Detalles Bibliográficos
Autores principales: Pacheco, Sarai, Marcet-Ortega, Marina, Lange, Julian, Jasin, Maria, Keeney, Scott, Roig, Ignasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358828/
https://www.ncbi.nlm.nih.gov/pubmed/25768017
http://dx.doi.org/10.1371/journal.pgen.1005017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358828/
https://www.ncbi.nlm.nih.gov/pubmed/25768017
http://dx.doi.org/10.1371/journal.pgen.1005017

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