Cargando…

The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes

Most mutations that compromise meiotic recombination or synapsis in mouse spermatocytes result in arrest and apoptosis at the pachytene stage of the first meiotic prophase. Two main mechanisms are thought to trigger arrest: one independent of the double-strand breaks (DSBs) that initiate meiotic rec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pacheco, Sarai, Marcet-Ortega, Marina, Lange, Julian, Jasin, Maria, Keeney, Scott, Roig, Ignasi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358828/ https://www.ncbi.nlm.nih.gov/pubmed/25768017 http://dx.doi.org/10.1371/journal.pgen.1005017

Ejemplares similares

p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes
por: Marcet-Ortega, Marina, et al.
Publicado: (2017)

ATR is required to complete meiotic recombination in mice
por: Pacheco, Sarai, et al.
Publicado: (2018)

Defects in meiotic recombination delay progression through pachytene in Tex19.1(−/−) mouse spermatocytes
por: Crichton, James H., et al.
Publicado: (2018)

Homeostatic control of recombination is implemented progressively in mouse meiosis
por: Cole, Francesca, et al.
Publicado: (2012)

The Molecular Chaperone Hsp90α Is Required for Meiotic Progression of Spermatocytes beyond Pachytene in the Mouse
por: Grad, Iwona, et al.
Publicado: (2010)

Comprehensive Analysis of the Transcriptome-Wide m6A Methylation in Mouse Pachytene Spermatocytes and Round Spermatids
por: Hong, Shihao, et al.
Publicado: (2022)

ATM Promotes the Obligate XY Crossover and both Crossover Control and Chromosome Axis Integrity on Autosomes
por: Barchi, Marco, et al.
Publicado: (2008)

Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination
por: Abreu, Carla M., et al.
Publicado: (2018)

Corrigendum: Comprehensive analysis of the transcriptome-wide m6A methylation in mouse pachytene spermatocytes and round spermatids
por: Hong, Shihao, et al.
Publicado: (2022)

Mouse TRIP13/PCH2 Is Required for Recombination and Normal Higher-Order Chromosome Structure during Meiosis
por: Roig, Ignasi, et al.
Publicado: (2010)

ATM controls meiotic double-strand break formation
por: Lange, Julian, et al.
Publicado: (2011)

Alkbh1 and Tzfp repress a non-repeat piRNA cluster in pachytene spermatocytes
por: Nordstrand, Line M., et al.
Publicado: (2012)

Transforming growth factor beta-1 decreases the yield of the second meiotic division of rat pachytene spermatocytes in vitro
por: Damestoy, Anne, et al.
Publicado: (2005)

Transient Protection from Heat-Stress Induced Apoptotic Stimulation by Metastasis-Associated Protein 1 in Pachytene Spermatocytes
por: Li, Wei, et al.
Publicado: (2011)

Effects of Fatty Acids on Intracellular [Ca(2+)], Mitochondrial Uncoupling and Apoptosis in Rat Pachytene Spermatocytes and Round Spermatids
por: Paillamanque, Joaquín, et al.
Publicado: (2016)

Linker histone variant H1t is closely associated with repressed repeat-element chromatin domains in pachytene spermatocytes
por: Mahadevan, Iyer Aditya, et al.
Publicado: (2020)

Mouse Pachytene Checkpoint 2 (Trip13) Is Required for Completing Meiotic Recombination but Not Synapsis
por: Li, Xin, et al.
Publicado: (2007)

Distinct Expression Profiles and Novel Targets of MicroRNAs in Human Spermatogonia, Pachytene Spermatocytes, and Round Spermatids between OA Patients and NOA Patients
por: Yao, Chencheng, et al.
Publicado: (2017)

Correction: Mouse Pachytene Checkpoint 2 (Trip13) Is Required for Completing Meiotic Recombination but Not Synapsis
por: Chenglin Li, Xin, et al.
Publicado: (2007)

Expression of Arf Tumor Suppressor in Spermatogonia Facilitates Meiotic Progression in Male Germ Cells
por: Churchman, Michelle L., et al.
Publicado: (2011)

The ATM signaling network in development and disease
por: Stracker, Travis H., et al.
Publicado: (2013)

Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics
por: Cole, Francesca, et al.
Publicado: (2014)

CENP-A binding domains and recombination patterns in horse spermatocytes
por: Cappelletti, Eleonora, et al.
Publicado: (2019)

Tex19.1 promotes Spo11-dependent meiotic recombination in mouse spermatocytes
por: Crichton, James H., et al.
Publicado: (2017)

p53 Controls Meiotic Prophase Progression and Crossover Formation
por: Marcet-Ortega, Marina, et al.
Publicado: (2022)

ATR is a multifunctional regulator of male mouse meiosis
por: Widger, Alexander, et al.
Publicado: (2018)

TCFL5 deficiency impairs the pachytene to diplotene transition during spermatogenesis in the mouse
por: Galán-Martínez, Javier, et al.
Publicado: (2022)

Local and sex-specific biases in crossover vs. noncrossover outcomes at meiotic recombination hot spots in mice
por: de Boer, Esther, et al.
Publicado: (2015)

How much is enough? Control of DNA double-strand break numbers in mouse meiosis
por: Kauppi, Liisa, et al.
Publicado: (2013)

A Global Expression Switch Marks Pachytene Initiation during Mouse Male Meiosis
por: Fallahi, Mohammad, et al.
Publicado: (2010)

YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis
por: Liu, Rong, et al.
Publicado: (2021)

Retinoic Acid Is Sufficient for the In Vitro Induction of Mouse Spermatocytes
por: Wang, Si, et al.
Publicado: (2016)

Negative heterosis for meiotic recombination rate in spermatocytes of the domestic chicken Gallus gallus
por: Malinovskaya, L.P., et al.
Publicado: (2021)

Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes
por: Ishiguro, Kei-ichiro, et al.
Publicado: (2014)

Robertsonian chromosomes and the nuclear architecture of mouse meiotic prophase spermatocytes
por: Berríos, Soledad, et al.
Publicado: (2014)

Uncoupling of transcriptomic and cytological differentiation in mouse spermatocytes with impaired meiosis
por: Fine, Alexander D., et al.
Publicado: (2019)

Therapeutic Dose of Hydroxyurea-Induced Synaptic Abnormalities on the Mouse Spermatocyte
por: Fan, Xiaobo, et al.
Publicado: (2021)

Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase
por: Wojtasz, Lukasz, et al.
Publicado: (2009)

Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and undergo pachytene chromatin inactivation?
por: Matveevsky, Sergey, et al.
Publicado: (2016)

A Mutation in Mtap2 Is Associated with Arrest of Mammalian Spermatocytes before the First Meiotic Division
por: Sun, Fengyun, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_po315i69osi7nut1gdtvsg5car