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RNA degradation in antiviral immunity and autoimmunity

Post-transcriptional control determines the fate of cellular RNA molecules. Nonsense-mediated decay (NMD) provides quality control of mRNA, targeting faulty cellular transcripts for degradation by multiple nucleases including the RNA exosome. Recent findings have revealed a role for NMD in targeting...

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Detalles Bibliográficos
Autores principales: Rigby, Rachel E., Rehwinkel, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358841/
https://www.ncbi.nlm.nih.gov/pubmed/25709093
http://dx.doi.org/10.1016/j.it.2015.02.001