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RNA degradation in antiviral immunity and autoimmunity
Post-transcriptional control determines the fate of cellular RNA molecules. Nonsense-mediated decay (NMD) provides quality control of mRNA, targeting faulty cellular transcripts for degradation by multiple nucleases including the RNA exosome. Recent findings have revealed a role for NMD in targeting...
Autores principales: | Rigby, Rachel E., Rehwinkel, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358841/ https://www.ncbi.nlm.nih.gov/pubmed/25709093 http://dx.doi.org/10.1016/j.it.2015.02.001 |
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