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RSV Vaccine-Enhanced Disease Is Orchestrated by the Combined Actions of Distinct CD4 T Cell Subsets

There is no currently licensed vaccine for respiratory syncytial virus (RSV) despite being the leading cause of lower respiratory tract infections in children. Children previously immunized with a formalin-inactivated RSV (FI-RSV) vaccine exhibited enhanced respiratory disease following natural RSV...

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Detalles Bibliográficos
Autores principales: Knudson, Cory J., Hartwig, Stacey M., Meyerholz, David K., Varga, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358888/
https://www.ncbi.nlm.nih.gov/pubmed/25769044
http://dx.doi.org/10.1371/journal.ppat.1004757