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Transient knockdown-mediated deficiency in plectin alters hepatocellular motility in association with activated FAK and Rac1-GTPase

BACKGROUND: Plectin is one of the cytolinker proteins that play a crucial role in maintaining the integrity of cellular architecture. It is a component of desmosome complexes connecting cytoskeletal proteins and trans-membrane molecules. In epithelial cells, plectin connects cytokeratins and integri...

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Detalles Bibliográficos
Autores principales: Cheng, Chiung-Chi, Lai, Yen-Chang Clark, Lai, Yih-Shyong, Hsu, Yung-Hsiang, Chao, Wei-Ting, Sia, Kee-Chin, Tseng, Yu-Hui, Liu, Yi-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358909/
https://www.ncbi.nlm.nih.gov/pubmed/25774093
http://dx.doi.org/10.1186/s12935-015-0177-1