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Transient knockdown-mediated deficiency in plectin alters hepatocellular motility in association with activated FAK and Rac1-GTPase
BACKGROUND: Plectin is one of the cytolinker proteins that play a crucial role in maintaining the integrity of cellular architecture. It is a component of desmosome complexes connecting cytoskeletal proteins and trans-membrane molecules. In epithelial cells, plectin connects cytokeratins and integri...
Autores principales: | Cheng, Chiung-Chi, Lai, Yen-Chang Clark, Lai, Yih-Shyong, Hsu, Yung-Hsiang, Chao, Wei-Ting, Sia, Kee-Chin, Tseng, Yu-Hui, Liu, Yi-Hsiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358909/ https://www.ncbi.nlm.nih.gov/pubmed/25774093 http://dx.doi.org/10.1186/s12935-015-0177-1 |
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