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Langevin dynamics simulations of charged model phosphatidylinositol lipids in the presence of diffusion barriers: toward an atomic level understanding of corralling of PIP(2) by protein fences in biological membranes
BACKGROUND: The polyvalent acidic lipid phosphatidylinositol, 4,5-bisphosphate (PIP(2)) is important for many cellular functions. It has been suggested that different pools of PIP(2) exist in the cytoplasmic leaflet of the plasma membrane, and that such pooling could play a role in the regulation of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358915/ https://www.ncbi.nlm.nih.gov/pubmed/25774289 http://dx.doi.org/10.1186/s13628-014-0013-3 |