Langevin dynamics simulations of charged model phosphatidylinositol lipids in the presence of diffusion barriers: toward an atomic level understanding of corralling of PIP(2) by protein fences in biological membranes

BACKGROUND: The polyvalent acidic lipid phosphatidylinositol, 4,5-bisphosphate (PIP(2)) is important for many cellular functions. It has been suggested that different pools of PIP(2) exist in the cytoplasmic leaflet of the plasma membrane, and that such pooling could play a role in the regulation of...

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Detalles Bibliográficos
Autores principales: Lee, Kyu Il, Im, Wonpil, Pastor, Richard W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358915/
https://www.ncbi.nlm.nih.gov/pubmed/25774289
http://dx.doi.org/10.1186/s13628-014-0013-3

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