Obesity Triggers Enhanced MDSC Accumulation in Murine Renal Tumors via Elevated Local Production of CCL2

Obesity is one of the leading risk factors for developing renal cell carcinoma, an immunogenic tumor that is treated clinically with immunostimulatory therapies. Currently, however, the mechanisms linking obesity with renal cancer incidence are unclear. Using a model of diet-induced obesity, we foun...

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Detalles Bibliográficos
Autores principales: Hale, Malika, Itani, Farah, Buchta, Claire M., Wald, Gal, Bing, Megan, Norian, Lyse A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358922/
https://www.ncbi.nlm.nih.gov/pubmed/25769110
http://dx.doi.org/10.1371/journal.pone.0118784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358922/
https://www.ncbi.nlm.nih.gov/pubmed/25769110
http://dx.doi.org/10.1371/journal.pone.0118784

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