Comparative Metabolic Analysis of CHO Cell Clones Obtained through Cell Engineering, for IgG Productivity, Growth and Cell Longevity

Cell engineering has been used to improve animal cells’ central carbon metabolism. Due to the central carbon metabolism’s inefficiency and limiting input of carbons into the TCA cycle, key reactions belonging to these pathways have been targeted to improve cultures’ performance. Previous works have...

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Detalles Bibliográficos
Autores principales: Wilkens, Camila A., Gerdtzen, Ziomara P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358941/
https://www.ncbi.nlm.nih.gov/pubmed/25768021
http://dx.doi.org/10.1371/journal.pone.0119053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358941/
https://www.ncbi.nlm.nih.gov/pubmed/25768021
http://dx.doi.org/10.1371/journal.pone.0119053

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