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Inducible and Reversible Lentiviral and Recombination Mediated Cassette Exchange (RMCE) Systems for Controlling Gene Expression

Manipulation of gene expression to invoke loss of function (LoF) or gain of function (GoF) phenotypes is important for interrogating complex biological questions both in vitro and in vivo. Doxycycline (Dox)-inducible gene expression systems are commonly used although success is often limited by high...

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Detalles Bibliográficos
Autores principales: Bersten, David C., Sullivan, Adrienne E., Li, Dian, Bhakti, Veronica, Bent, Stephen J., Whitelaw, Murray L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358958/
https://www.ncbi.nlm.nih.gov/pubmed/25768837
http://dx.doi.org/10.1371/journal.pone.0116373