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Clonality and Evolutionary History of Rhabdomyosarcoma

To infer the subclonality of rhabdomyosarcoma (RMS) and predict the temporal order of genetic events for the tumorigenic process, and to identify novel drivers, we applied a systematic method that takes into account germline and somatic alterations in 44 tumor-normal RMS pairs using deep whole-genom...

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Detalles Bibliográficos
Autores principales: Chen, Li, Shern, Jack F., Wei, Jun S., Yohe, Marielle E., Song, Young K., Hurd, Laura, Liao, Hongling, Catchpoole, Daniel, Skapek, Stephen X., Barr, Frederic G., Hawkins, Douglas S., Khan, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358975/
https://www.ncbi.nlm.nih.gov/pubmed/25768946
http://dx.doi.org/10.1371/journal.pgen.1005075