Structure-Based Virtual Screening and Discovery of New PPARδ/γ Dual Agonist and PPARδ and γ Agonists

Peroxisome proliferator-activated receptors (PPARs) are involved in the control of carbohydrate and lipid metabolism and are considered important targets to treat diabetes mellitus and metabolic syndrome. The available PPAR ligands have several side effects leading to health risks justifying the sea...

Descripción completa

Detalles Bibliográficos
Autores principales: Maltarollo, Vinicius G., Togashi, Marie, Nascimento, Alessandro S., Honorio, Kathia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358979/
https://www.ncbi.nlm.nih.gov/pubmed/25767888
http://dx.doi.org/10.1371/journal.pone.0118790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358979/
https://www.ncbi.nlm.nih.gov/pubmed/25767888
http://dx.doi.org/10.1371/journal.pone.0118790

Ejemplares similares