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Human Adipose Cells In Vitro Are Either Refractory or Responsive to Insulin, Reflecting Host Metabolic State

While intercellular communication processes are frequently characterized by switch-like transitions, the endocrine system, including the adipose tissue response to insulin, has been characterized by graded responses. Yet here individual cells from adipose tissue biopsies are best described by a swit...

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Detalles Bibliográficos
Autores principales: Lizunov, Vladimir A., Stenkula, Karin G., Blank, Paul S., Troy, Aaron, Lee, Jo-Ping, Skarulis, Monica C., Cushman, Samuel W., Zimmerberg, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359092/
https://www.ncbi.nlm.nih.gov/pubmed/25768970
http://dx.doi.org/10.1371/journal.pone.0119291