Differences in Type I Interferon Signaling Antagonism by Dengue Viruses in Human and Non-Human Primate Cell Lines

BACKGROUND/OBJECTIVES: In vitro studies have shown that dengue virus (DENV) can thwart the actions of interferon (IFN)-α/β and prevent the development of an antiviral state in infected cells. Clinical studies looking at gene expression in patients with severe dengue show a reduced expression of inte...

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Detalles Bibliográficos
Autores principales: Medina, Freddy A., Torres-Malavé, Giselle, Chase, Amanda J., Santiago, Gilberto A., Medina, Juan F., Santiago, Luis M., Muñoz-Jordán, Jorge L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359095/
https://www.ncbi.nlm.nih.gov/pubmed/25768016
http://dx.doi.org/10.1371/journal.pntd.0003468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359095/
https://www.ncbi.nlm.nih.gov/pubmed/25768016
http://dx.doi.org/10.1371/journal.pntd.0003468

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