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Iron Prevents the Development of Experimental Cerebral Malaria by Attenuating CXCR3-Mediated T Cell Chemotaxis

Cerebral malaria is a severe neurological complication of Plasmodium falciparum infection. Previous studies have suggested that iron overload can suppress the generation of a cytotoxic immune response; however, the effect of iron on experimental cerebral malaria (ECM) is yet unknown. Here we determi...

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Detalles Bibliográficos
Autores principales: Van Den Ham, Kristin M., Shio, Marina Tiemi, Rainone, Anthony, Fournier, Sylvie, Krawczyk, Connie M., Olivier, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359107/
https://www.ncbi.nlm.nih.gov/pubmed/25768944
http://dx.doi.org/10.1371/journal.pone.0118451