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NatB Domain-Containing CRA-1 Antagonizes Hydrolase ACER-1 Linking Acetyl-CoA Metabolism to the Initiation of Recombination during C. elegans Meiosis

The formation of DNA double-strand breaks (DSBs) must take place during meiosis to ensure the formation of crossovers, which are required for accurate chromosome segregation, therefore avoiding aneuploidy. However, DSB formation must be tightly regulated to maintain genomic integrity. How this regul...

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Detalles Bibliográficos
Autores principales: Gao, Jinmin, Kim, Hyun-Min, Elia, Andrew E., Elledge, Stephen J., Colaiácovo, Monica P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359108/
https://www.ncbi.nlm.nih.gov/pubmed/25768301
http://dx.doi.org/10.1371/journal.pgen.1005029