Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma

Melanoma is often caused by mutations due to exposure to ultraviolet radiation. This study reports a recurrent somatic C > T change causing a P131L mutation in the RQCD1 (Required for Cell Differentiation1 Homolog) gene identified through whole exome sequencing of 20 metastatic melanomas. Screeni...

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Detalles Bibliográficos
Autores principales: Wong, Stephen Q., Behren, Andreas, Mar, Victoria J., Woods, Katherine, Li, Jason, Martin, Claire, Sheppard, Karen E., Wolfe, Rory, Kelly, John, Cebon, Jonathan, Dobrovic, Alexander, McArthur, Grant A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359221/
https://www.ncbi.nlm.nih.gov/pubmed/25544760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359221/
https://www.ncbi.nlm.nih.gov/pubmed/25544760

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