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Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts

Stromal fibroblasts become altered in response to solid cancers, to exhibit myofibroblastic characteristics, with disease promoting influence. Infiltrating mesenchymal stem cells (MSC) may contribute towards these changes, but the factors secreted by cancer cells that impact MSC differentiation are...

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Detalles Bibliográficos
Autores principales: Chowdhury, Ridwana, Webber, Jason P., Gurney, Mark, Mason, Malcolm D., Tabi, Zsuzsanna, Clayton, Aled
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359250/
https://www.ncbi.nlm.nih.gov/pubmed/25596732