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Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts
Stromal fibroblasts become altered in response to solid cancers, to exhibit myofibroblastic characteristics, with disease promoting influence. Infiltrating mesenchymal stem cells (MSC) may contribute towards these changes, but the factors secreted by cancer cells that impact MSC differentiation are...
Autores principales: | Chowdhury, Ridwana, Webber, Jason P., Gurney, Mark, Mason, Malcolm D., Tabi, Zsuzsanna, Clayton, Aled |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359250/ https://www.ncbi.nlm.nih.gov/pubmed/25596732 |
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