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Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors

Epithelial-mesenchymal transition (EMT) plays a critical role in the development of tumor metastases by enhancing migration/invasion. One of the hallmarks of EMT is loss of E-cadherin and gain of N-cadherin expression, which are regulated by the core EMT-inducing transcription factors (EMT-TFs), suc...

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Detalles Bibliográficos
Autores principales: Xu, Ming, Zhu, Changhong, Zhao, Xian, Chen, Cheng, Zhang, Hailong, Yuan, Haihua, Deng, Rong, Dou, Jinzhuo, Wang, Yanli, Huang, Jian, Chen, Qin, Jiang, Bin, Yu, Jianxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359269/
https://www.ncbi.nlm.nih.gov/pubmed/25460509