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Knockdown of IL-1β Improves Hypoxia–ischemia Brain Associated with IL-6 Up-regulation in Cell and Animal Models

A study was conducted to investigate the effect of interleukin-1β (IL-1β) on hypoxia ischemia (HI) of cultured astrocyte and neonatal rat models and to explore the underlying molecular regulation mechanism. Primary rat astrocyte was exposed to hypoxia (2 % O(2), 98 % N(2)) and cultured in serum-free...

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Detalles Bibliográficos
Autores principales: Liu, Sujuan, Zhu, Shengyun, Zou, Yu, Wang, Tinghua, Fu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359286/
https://www.ncbi.nlm.nih.gov/pubmed/24965599
http://dx.doi.org/10.1007/s12035-014-8764-z