Pan-PPAR Modulation Effectively Protects APP/PS1 Mice from Amyloid Deposition and Cognitive Deficits

Alzheimer’s disease (AD) is a neurodegenerative condition that leads to neuronal death and memory dysfunction. In the past, specific peroxisome proliferator-activated receptor (PPAR)γ-agonists, such as pioglitazone, have been tested with limited success to improve AD pathology. Here, we investigated...

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Detalles Bibliográficos
Autores principales: Kummer, Markus P., Schwarzenberger, Rafael, Sayah-Jeanne, Sakina, Dubernet, Mathieu, Walczak, Robert, Hum, Dean W., Schwartz, Stephanie, Axt, Daisy, Heneka, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359287/
https://www.ncbi.nlm.nih.gov/pubmed/24838579
http://dx.doi.org/10.1007/s12035-014-8743-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359287/
https://www.ncbi.nlm.nih.gov/pubmed/24838579
http://dx.doi.org/10.1007/s12035-014-8743-4

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