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Amyloid accumulation is a late event in sporadic Alzheimer's disease-like pathology in nontransgenic rats

The amyloid cascade hypothesis posits that deposition of the amyloid β (Aβ) peptide in the brain is a key event in the initiation of Alzheimer's disease (AD). Nonetheless, it now seems increasingly unlikely that amyloid toxicity is the cause of sporadic AD, which leads to cognitive decline. Her...

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Detalles Bibliográficos
Autores principales: Stefanova, Natalia A., Muraleva, Natalia A., Korbolina, Elena E., Kiseleva, Elena, Maksimova, Kseniya Yi., Kolosova, Nataliya G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359302/
https://www.ncbi.nlm.nih.gov/pubmed/25595891