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Helicobacter pylori bacteria alter the p53 stress response via Erk-HDM2 pathway

H. pylori infection is the strongest known risk factor for gastric cancer. Inhibition of host tumor suppressor mechanisms by the bacteria underlies the development of this disease. Among the tumor suppressors affected by H. pylori are p53 and E-cadherin, which inhibition has been shown to increase t...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Vikas, Noto, Jennifer M., Wei, Jinxiong, Andl, Claudia, El-Rifai, Wael, Peek, Richard M., Zaika, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359312/
https://www.ncbi.nlm.nih.gov/pubmed/25605238