Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells

Carnosic acid is a phenolic diterpene from rosmarinus officinalis, and has multiple functions, such as anti-inflammatory, anti-viral, and anti-tumor activity. In this study, we examined whether carnosic acid could sensitize TRAIL-mediated apoptosis in human renal carcinoma Caki cells. We found that...

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Detalles Bibliográficos
Autores principales: Jung, Kyong-Jin, Min, Kyoung-jin, Bae, Jae Hoon, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359314/
https://www.ncbi.nlm.nih.gov/pubmed/25596735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359314/
https://www.ncbi.nlm.nih.gov/pubmed/25596735

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