Lateral inhibition of Notch signaling in neoplastic cells

During normal development, heterogeneous expression of Notch ligands can result in pathway suppression in the signal-sending cell, a process known as lateral inhibition. It is unclear if an analogous phenomenon occurs in malignant cells. We observed significant induction of Notch ligands in glioblas...

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Detalles Bibliográficos
Autores principales: Lim, Kah Jing, Brandt, William D., Heth, Jason A., Muraszko, Karin M., Fan, Xing, Bar, Eli E., Eberhart, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359323/
https://www.ncbi.nlm.nih.gov/pubmed/25557173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359323/
https://www.ncbi.nlm.nih.gov/pubmed/25557173

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