Cargando…

Lateral inhibition of Notch signaling in neoplastic cells

During normal development, heterogeneous expression of Notch ligands can result in pathway suppression in the signal-sending cell, a process known as lateral inhibition. It is unclear if an analogous phenomenon occurs in malignant cells. We observed significant induction of Notch ligands in glioblas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lim, Kah Jing, Brandt, William D., Heth, Jason A., Muraszko, Karin M., Fan, Xing, Bar, Eli E., Eberhart, Charles G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359323/ https://www.ncbi.nlm.nih.gov/pubmed/25557173

Ejemplares similares

Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres
por: Ding, Dacheng, et al.
Publicado: (2014)

Hypoxia Promotes Uveal Melanoma Invasion through Enhanced Notch and MAPK Activation
por: Asnaghi, Laura, et al.
Publicado: (2014)

Tenascin-C: A Novel Candidate Marker for Cancer Stem Cells in Glioblastoma Identified by Tissue Microarrays
por: Nie, Song, et al.
Publicado: (2014)

Delta-Notch signaling and lateral inhibition in zebrafish spinal cord development
por: Appel, Bruce, et al.
Publicado: (2001)

Targeting Notch signaling as a novel therapy for retinoblastoma
por: Asnaghi, Laura, et al.
Publicado: (2016)

Neoplastic cells are a rare component in human glioblastoma microvasculature
por: Rodriguez, Fausto J., et al.
Publicado: (2012)

Delta-Notch signaling and lateral inhibition in zebrafish spinal cord development: Correction
por: Appel, Bruce, et al.
Publicado: (2002)

Coordinated control of Notch/Delta signalling and cell cycle progression drives lateral inhibition-mediated tissue patterning
por: Hunter, Ginger L., et al.
Publicado: (2016)

Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis
por: Ma, Xiaoxing, et al.
Publicado: (2017)

Selenite Inhibits Notch Signaling in Cells and Mice
por: Powers, Michael, et al.
Publicado: (2021)

A new model of Notch signalling: Control of Notch receptor cis-inhibition via Notch ligand dimers
por: Chen, Daipeng, et al.
Publicado: (2023)

Signalling Antibodies for the Treatment of Neoplastic Disease
por: Glennie, M. J.
Publicado: (2000)

Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors
por: Aste-Amézaga, Miguel, et al.
Publicado: (2010)

Enhanced Delta-Notch Lateral Inhibition Model Incorporating Intracellular Notch Heterogeneity and Tension-Dependent Rate of Delta-Notch Binding that Reproduces Sprouting Angiogenesis Patterns
por: Koon, Yen Ling, et al.
Publicado: (2018)

Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls
por: Ristori, Tommaso, et al.
Publicado: (2020)

Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression
por: Voss, Dillon M., et al.
Publicado: (2017)

Inhibition of Notch Signaling Promotes the Differentiation of Epicardial Progenitor Cells into Adipocytes
por: Liu, Bin, et al.
Publicado: (2021)

Inhibition of apoptosis by Notch signalling in breast epithelial cells
por: Meurette, O, et al.
Publicado: (2008)

Dishevelled limits Notch signalling through inhibition of CSL
por: Collu, Giovanna M., et al.
Publicado: (2012)

Inhibition of TGF-β and NOTCH Signaling by Cutaneous Papillomaviruses
por: Meyers, Jordan M., et al.
Publicado: (2018)

Inhibition of Notch Signaling in Combination with Paclitaxel Reduces Platinum-Resistant Ovarian Tumor Growth
por: Groeneweg, Jolijn W., et al.
Publicado: (2014)

Relevance of Notch Signaling for Bone Metabolism and Regeneration
por: Ballhause, Tobias M., et al.
Publicado: (2021)

Collagen molecular phenotypic switch between non-neoplastic and neoplastic canine mammary tissues
por: Terajima, Masahiko, et al.
Publicado: (2021)

Neuritin Inhibits Notch Signaling through Interacted with Neuralized to Promote the Neurite Growth
por: Zhang, Pan, et al.
Publicado: (2017)

Notch signaling in lung diseases: focus on Notch1 and Notch3
por: Zong, Dandan, et al.
Publicado: (2016)

Ferulic Acid: A Natural Phenol That Inhibits Neoplastic Events through Modulation of Oncogenic Signaling
por: Singh Tuli, Hardeep, et al.
Publicado: (2022)

Inhibition of the growth of transformed and neoplastic cells by the dipeptide carnosine.
por: Holliday, R., et al.
Publicado: (1996)

Xanthohumol Inhibits Notch Signaling and Induces Apoptosis in Hepatocellular Carcinoma
por: Kunnimalaiyaan, Selvi, et al.
Publicado: (2015)

Galectin-3 Inhibits Osteoblast Differentiation through Notch Signaling()()
por: Nakajima, Kosei, et al.
Publicado: (2014)

Inhibition of Delta-induced Notch signaling using fucose analogs
por: Schneider, Michael, et al.
Publicado: (2017)

Inhibition of Notch signaling rescues cardiovascular development in Kabuki Syndrome
por: Serrano, Maria de los Angeles, et al.
Publicado: (2019)

MET Inhibition Sensitizes Rhabdomyosarcoma Cells to NOTCH Signaling Suppression
por: Perrone, Clara, et al.
Publicado: (2022)

Inhibition of Wnt signalling by Notch via two distinct mechanisms
por: Acar, Ahmet, et al.
Publicado: (2021)

Nrf2 in Neoplastic and Non-Neoplastic Liver Diseases
por: Orrù, Claudia, et al.
Publicado: (2020)

Increased Notch signaling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells
por: Kwon, Oh-Joon, et al.
Publicado: (2014)

Vascular Notch Signaling in Stress Hematopoiesis
por: Huang, Can, et al.
Publicado: (2021)

Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes
por: Ho, L, et al.
Publicado: (2013)

Screening of cytochrome 4Z1 expression in human non-neoplastic, pre-neoplastic and neoplastic tissues
por: Al-saraireh, Yousef M, et al.
Publicado: (2020)

The adhesion force of Notch with Delta and the rate of Notch signaling
por: Ahimou, Francois, et al.
Publicado: (2004)

Notching on Cancer’s Door: Notch Signaling in Brain Tumors
por: Teodorczyk, Marcin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_9p88skneg2g9p9gaaqbs3796sc