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The identification of trans-associations between prostate cancer GWAS SNPs and RNA expression differences in tumor-adjacent stroma

Here we tested the hypothesis that SNPs associated with prostate cancer risk, might differentially affect RNA expression in prostate cancer stroma. The most significant 35 SNP loci were selected from Genome Wide Association (GWA) studies of ~40,000 patients. We also selected 4030 transcripts previou...

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Detalles Bibliográficos
Autores principales: Chen, Xin, McClelland, Michael, Jia, Zhenyu, Rahmatpanah, Farah B., Sawyers, Anne, Trent, Jeffrey, Duggan, David, Mercola, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359337/
https://www.ncbi.nlm.nih.gov/pubmed/25638161