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Agonist binding by the β(2)-adrenergic receptor: an effect of receptor conformation on ligand association–dissociation characteristics

The β(2)-adrenergic receptor (β(2)-AR), a G protein-coupled receptor (GPCR), is a physiologically important transmembrane protein that is a target for drugs used for treatment of asthma and cardiovascular diseases. Study of the first steps of ligand recognition and the molecular basis of ligand bind...

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Detalles Bibliográficos
Autores principales: Plazinska, Anita, Plazinski, Wojciech, Jozwiak, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359354/
https://www.ncbi.nlm.nih.gov/pubmed/25726162
http://dx.doi.org/10.1007/s00249-015-1010-4