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Agonist binding by the β(2)-adrenergic receptor: an effect of receptor conformation on ligand association–dissociation characteristics
The β(2)-adrenergic receptor (β(2)-AR), a G protein-coupled receptor (GPCR), is a physiologically important transmembrane protein that is a target for drugs used for treatment of asthma and cardiovascular diseases. Study of the first steps of ligand recognition and the molecular basis of ligand bind...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359354/ https://www.ncbi.nlm.nih.gov/pubmed/25726162 http://dx.doi.org/10.1007/s00249-015-1010-4 |