MicroRNA-mediated repression of nonsense mRNAs

Numerous studies have established important roles for microRNAs (miRNAs) in regulating gene expression. Here, we report that miRNAs also serve as a surveillance system to repress the expression of nonsense mRNAs that may produce harmful truncated proteins. Upon recognition of the premature terminati...

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Detalles Bibliográficos
Autores principales: Zhao, Ya, Lin, Jimin, Xu, Beiying, Hu, Sida, Zhang, Xue, Wu, Ligang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359369/
https://www.ncbi.nlm.nih.gov/pubmed/25107276
http://dx.doi.org/10.7554/eLife.03032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359369/
https://www.ncbi.nlm.nih.gov/pubmed/25107276
http://dx.doi.org/10.7554/eLife.03032

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