TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation

The functions of the TAF subunits of mammalian TFIID in physiological processes remain poorly characterised. In this study, we describe a novel function of TAFs in directing genomic occupancy of a transcriptional activator. Using liver-specific inactivation in mice, we show that the TAF4 subunit of...

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Detalles Bibliográficos
Autores principales: Alpern, Daniil, Langer, Diana, Ballester, Benoit, Le Gras, Stephanie, Romier, Christophe, Mengus, Gabrielle, Davidson, Irwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359380/
https://www.ncbi.nlm.nih.gov/pubmed/25209997
http://dx.doi.org/10.7554/eLife.03613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359380/
https://www.ncbi.nlm.nih.gov/pubmed/25209997
http://dx.doi.org/10.7554/eLife.03613

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