BitPhylogeny: a probabilistic framework for reconstructing intra-tumor phylogenies

Cancer has long been understood as a somatic evolutionary process, but many details of tumor progression remain elusive. Here, we present BitPhylogeny, a probabilistic framework to reconstruct intra-tumor evolutionary pathways. Using a full Bayesian approach, we jointly estimate the number and compo...

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Detalles Bibliográficos
Autores principales: Yuan, Ke, Sakoparnig, Thomas, Markowetz, Florian, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359483/
https://www.ncbi.nlm.nih.gov/pubmed/25786108
http://dx.doi.org/10.1186/s13059-015-0592-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359483/
https://www.ncbi.nlm.nih.gov/pubmed/25786108
http://dx.doi.org/10.1186/s13059-015-0592-6

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