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BitPhylogeny: a probabilistic framework for reconstructing intra-tumor phylogenies
Cancer has long been understood as a somatic evolutionary process, but many details of tumor progression remain elusive. Here, we present BitPhylogeny, a probabilistic framework to reconstruct intra-tumor evolutionary pathways. Using a full Bayesian approach, we jointly estimate the number and compo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359483/ https://www.ncbi.nlm.nih.gov/pubmed/25786108 http://dx.doi.org/10.1186/s13059-015-0592-6 |