Cargando…

Erk2 but not Erk1 regulates crosstalk between Met and EGFR in squamous cell carcinoma cell lines

BACKGROUND: Squamous cell carcinoma (SCC) is the most common type of tongue and larynx cancer and a common type of lung cancer. In this study, we attempted to specifically evaluate the signaling pathway underlying HGF/Met induced EGFR ligand release in SSCs. The Met proto-oncogene encodes for a tyro...

Descripción completa

Detalles Bibliográficos
Autores principales: Gusenbauer, Simone, Zanucco, Emanuele, Knyazev, Pjotr, Ullrich, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359546/
https://www.ncbi.nlm.nih.gov/pubmed/25884419
http://dx.doi.org/10.1186/s12943-015-0319-z