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Erk2 but not Erk1 regulates crosstalk between Met and EGFR in squamous cell carcinoma cell lines
BACKGROUND: Squamous cell carcinoma (SCC) is the most common type of tongue and larynx cancer and a common type of lung cancer. In this study, we attempted to specifically evaluate the signaling pathway underlying HGF/Met induced EGFR ligand release in SSCs. The Met proto-oncogene encodes for a tyro...
Autores principales: | Gusenbauer, Simone, Zanucco, Emanuele, Knyazev, Pjotr, Ullrich, Axel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359546/ https://www.ncbi.nlm.nih.gov/pubmed/25884419 http://dx.doi.org/10.1186/s12943-015-0319-z |
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