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TRPA1 as a drug target—promise and challenges

The transient receptor potential ankyrin 1 (TRPA1) channel is a nonselective cation channel belonging to the superfamily of transient receptor potential (TRP) channels. It is predominantly expressed in sensory neurons and serves as an irritant sensor for a plethora of electrophilic compounds. Recent...

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Detalles Bibliográficos
Autores principales: Chen, Jun, Hackos, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359712/
https://www.ncbi.nlm.nih.gov/pubmed/25640188
http://dx.doi.org/10.1007/s00210-015-1088-3