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Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development

Ionizing radiation is a potent activator of the tumor suppressor gene p53, which itself regulates the transcription of genes involved in canonical pathways such as the cell cycle, DNA repair and apoptosis as well as other biological processes like metabolism, autophagy, differentiation and developme...

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Detalles Bibliográficos
Autores principales: Quintens, Roel, Verreet, Tine, Janssen, Ann, Neefs, Mieke, Leysen, Liselotte, Michaux, Arlette, Verslegers, Mieke, Samari, Nada, Pani, Giuseppe, Verheyde, Joris, Baatout, Sarah, Benotmane, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359739/
https://www.ncbi.nlm.nih.gov/pubmed/25681390
http://dx.doi.org/10.1242/bio.20149969