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Plk4-dependent phosphorylation of STIL is required for centriole duplication

Duplication of centrioles, namely the formation of a procentriole next to the parental centriole, is regulated by the polo-like kinase Plk4. Only a few other proteins, including STIL (SCL/TAL1 interrupting locus, SIL) and Sas-6, are required for the early step of centriole biogenesis. Following Plk4...

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Detalles Bibliográficos
Autores principales: Kratz, Anne-Sophie, Bärenz, Felix, Richter, Kai T., Hoffmann, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359743/
https://www.ncbi.nlm.nih.gov/pubmed/25701666
http://dx.doi.org/10.1242/bio.201411023