Cargando…

BRCA1 functions as a novel transcriptional cofactor in HIV-1 infection

BACKGROUND: Viruses have naturally evolved elegant strategies to manipulate the host’s cellular machinery, including ways to hijack cellular DNA repair proteins to aid in their own replication. Retroviruses induce DNA damage through integration of their genome into host DNA. DNA damage signaling pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Guendel, Irene, Meltzer, Beatrix W, Baer, Alan, Dever, Seth M, Valerie, Kristoffer, Guo, Jia, Wu, Yuntao, Kehn-Hall, Kylene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359766/
https://www.ncbi.nlm.nih.gov/pubmed/25879655
http://dx.doi.org/10.1186/s12985-015-0266-8