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Local administration of a novel Toll-like receptor 7 agonist in combination with doxorubicin induces durable tumouricidal effects in a murine model of T cell lymphoma

BACKGROUND: Conventional chemotherapy and radiotherapy for the treatment of lymphoma have notable drawbacks, and passive immunotherapy using a monoclonal antibody is restricted to CD20-positive B cell lymphoma. Therefore, new treatment types are urgently required, especially for T cell lymphoma. One...

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Detalles Bibliográficos
Autores principales: Zhu, Jiang, He, Shiping, Du, Jie, Wang, Zhulin, Li, Wang, Chen, Xianxiong, Jiang, Wenqi, Zheng, Duo, Jin, Guangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359787/
https://www.ncbi.nlm.nih.gov/pubmed/25887995
http://dx.doi.org/10.1186/s13045-015-0121-9