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Effective Binding of a Phosphatidylserine-Targeting Antibody to Ebola Virus Infected Cells and Purified Virions

Ebola virus is responsible for causing severe hemorrhagic fevers, with case fatality rates of up to 90%. Currently, no antiviral or vaccine is licensed against Ebola virus. A phosphatidylserine-targeting antibody (PGN401, bavituximab) has previously been shown to have broad-spectrum antiviral activi...

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Detalles Bibliográficos
Autores principales: Dowall, S. D., Graham, V. A., Corbin-Lickfett, K., Empig, C., Schlunegger, K., Bruce, C. B., Easterbrook, L., Hewson, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359806/
https://www.ncbi.nlm.nih.gov/pubmed/25815346
http://dx.doi.org/10.1155/2015/347903