Oxaliplatin Analogues with Carboxy Derivatives of Boldine with Enhanced Antioxidant Activity

A new oxaliplatin analog [Pt(dach)(L5)] (1) was synthesized and characterized as a continuation of a study of the previously reported [Pt(dach)(L6)] (2), where dach = (1R,2R)-diaminocyclohexane, L5 = 3-carboxyboldine, and L6 = 3-carboxypredicentrine. Compounds 1 and 2 exhibited a substantially enhan...

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Detalles Bibliográficos
Autores principales: Mellado, Marco, Jara, Carlos, Astudillo, David, Villena, Joan, Reveco, Patricio G., Thomet, Franz A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359857/
https://www.ncbi.nlm.nih.gov/pubmed/25814916
http://dx.doi.org/10.1155/2015/920143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359857/
https://www.ncbi.nlm.nih.gov/pubmed/25814916
http://dx.doi.org/10.1155/2015/920143

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