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Actin depolymerisation and crosslinking join forces with myosin II to contract actin coats on fused secretory vesicles

In many secretory cells actin and myosin are specifically recruited to the surface of secretory granules following their fusion with the plasma membrane. Actomyosin-dependent compression of fused granules is essential to promote active extrusion of cargo. However, little is known about molecular mec...

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Detalles Bibliográficos
Autores principales: Miklavc, Pika, Ehinger, Konstantin, Sultan, Ayesha, Felder, Tatiana, Paul, Patrick, Gottschalk, Kay-Eberhard, Frick, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359923/
https://www.ncbi.nlm.nih.gov/pubmed/25637593
http://dx.doi.org/10.1242/jcs.165571