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Behavioral Effects of the Benzodiazepine-Positive Allosteric Modulator SH-053-2’F-S-CH(3) in an Immune-Mediated Neurodevelopmental Disruption Model

BACKGROUND: Impaired γ-aminobutyric acid (GABA) signaling may contribute to the emergence of cognitive deficits and subcortical dopaminergic hyperactivity in patients with schizophrenia and related psychotic disorders. Against this background, it has been proposed that pharmacological interventions...

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Detalles Bibliográficos
Autores principales: Richetto, Juliet, Labouesse, Marie A., Poe, Michael M., Cook, James M., Grace, Anthony A., Riva, Marco A., Meyer, Urs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360215/
https://www.ncbi.nlm.nih.gov/pubmed/25636893
http://dx.doi.org/10.1093/ijnp/pyu055