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FKBP5 Genotype-Dependent DNA Methylation and mRNA Regulation After Psychosocial Stress in Remitted Depression and Healthy Controls

BACKGROUND: Polymorphisms in the FK506 binding protein 5 (FKBP5) gene have been shown to influence glucocorticoid receptor sensitivity, stress response regulation, and depression risk in traumatized subjects, with most consistent findings reported for the functional variant rs1360780. In the present...

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Detalles Bibliográficos
Autores principales: Höhne, Nina, Poidinger, Maximilian, Merz, Franziska, Pfister, Hildegard, Brückl, Tanja, Zimmermann, Petra, Uhr, Manfred, Holsboer, Florian, Ising, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360217/
https://www.ncbi.nlm.nih.gov/pubmed/25522420
http://dx.doi.org/10.1093/ijnp/pyu087