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FKBP5 Genotype-Dependent DNA Methylation and mRNA Regulation After Psychosocial Stress in Remitted Depression and Healthy Controls
BACKGROUND: Polymorphisms in the FK506 binding protein 5 (FKBP5) gene have been shown to influence glucocorticoid receptor sensitivity, stress response regulation, and depression risk in traumatized subjects, with most consistent findings reported for the functional variant rs1360780. In the present...
Autores principales: | Höhne, Nina, Poidinger, Maximilian, Merz, Franziska, Pfister, Hildegard, Brückl, Tanja, Zimmermann, Petra, Uhr, Manfred, Holsboer, Florian, Ising, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360217/ https://www.ncbi.nlm.nih.gov/pubmed/25522420 http://dx.doi.org/10.1093/ijnp/pyu087 |
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