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Lurasidone Exerts Antidepressant Properties in the Chronic Mild Stress Model through the Regulation of Synaptic and Neuroplastic Mechanisms in the Rat Prefrontal Cortex

BACKGROUND: Major depression is associated with several alterations, including reduced neuronal plasticity and impaired synaptic function, which represent an important target of pharmacological intervention. METHODS: In the present study, we have investigated the ability of the antipsychotic drug lu...

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Detalles Bibliográficos
Autores principales: Luoni, Alessia, Macchi, Flavia, Papp, Mariusz, Molteni, Raffaella, Riva, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360224/
https://www.ncbi.nlm.nih.gov/pubmed/25522402
http://dx.doi.org/10.1093/ijnp/pyu061